This book builds the framework for scientific research with in-depth analyses of major scientific theories. It carries paradigm unification from conceptualization in the first two chapters to realism in the in depth analysis. Data for each study include: the researchers method of analysis, and selection of paradigm(s), comparisons, contrasts, and a summary that follows with perspectives of normal science and naturalistic inquiry. It provides a structure for in-depth comparisons and contrasts of major paradigms-positivism, post-positivism, critical theory, and constructivism.