The Science of Getting Rich explains how to overcome mental barriers, and how creation, rather than competition, is the hidden key to wealth attraction. The book is divided into 17 short, straight-to-the-point chapters that are focused on business prosperity, mind training, and success in the material world. Through positivity and self-affirmation, the individual is empowered to attract what they want out of life.

Wallace Wattles descended from the mental healing movement in the mid-19th century. Through his personal study and experimentation Wattles claimed to have discovered the truth of New Thought principles and put them into practice in his own life. He practiced the technique of creative visualization, forming a visual image, and then working towards the realization of this vision. The Science of Getting Rich was credited by Rhonda Byrne as one of the inspirations for her popular 2006 film and 2007 book The Secret.

This case laminate collector's edition includes a Victorian inspired dust-jacket.