In The End of the Republican Era, Theodore J. Lowi predicts not only a collapse of the Republican coalition but also the potential collapse of the United States' republican experiment at large. Professing that the ideologies of dominant political coalitions contain the seeds of their own destruction, Lowi suggests that the efforts of a new conservative Right to enforce a national, religion-based morality has brought about the demise of the Republican era.

A new, in-depth afterword by Lowi brings the text up to date with a discussion of political events since the book's original publication. Noting the appearance of the new Conservative coalition, whose ideology runs counter to that of the traditional Republican party, Lowi affirms that the Republican era did in fact come to an end during the 1990s, having morphed into a Conservative party.