Edited by Jesse M. Pines, MD, MBA, MSCE is the National Director of Clinical Innovation at US Acute Care Solutions and a Professor of Emergency Medicine at Drexel University. He is board-certified in emergency medicine. Fernanda Bellolio, MD, MSc is the Chair for Research and a Professor of Emergency Medicine in the Department of Emergency Medicine at the Mayo Clinic. She is board-certified in emergency medicine. Christopher R. Carpenter, MD, MSc is the Director of Evidence Based Medicine and a Professor of Emergency Medicine in the Division of Emergency Medicine at Barnes Jewish Hospital at Washington University. He is board-certified in emergency medicine. Ali S. Raja, MD, MBA, MPH is Executive Vice Chair of the Department of Emergency Medicine at Massachusetts General Hospital and a Professor of Emergency Medicine at Harvard Medical School. He is board-certified in emergency medicine and clinical informatics.