Professor Harald H.H.W. Schmidt is a German physician and pharmacist, chairing the Department of Pharmacology and Personalized Medicine, Faculty of Health, Medicine and Life Sciences, at the University of Maastricht. Netherlands.After his double degree in medicine and pharmacy, he distinguished himself as an internationally highly recognized researcher in the fields of drug therapy, elucidation of the causes of disease and prevention.He headed and heads various research programs as an Advanced Investigator of the European Research Council (ERC), coordinator of Horizon 2020 project REPO-TRIAL and Collaboration on Science and Technology (COST) actions.He founded companies with which he brought therapeutics and diagnostics to market, is co-editor of the journal Network and Systems Medicine, and has written over 200 peer-reviewed international publications, reviews and books with a Hirsch factor of 92 and over 30,000 citations.Part of his early research training he conducted in the USA with the later Nobel Laureate, Ferid Murad, and led international institutes and research centers in Germany, Australia and the Netherlands. He is also the editor of a textbook on drug therapy and several expert handbooks in drug therapy.As a broadly experience and critical analyst, he recognized the fundamental conceptual crisis in medicine and became one of the pioneers of systems medicine, i.e. a complete redefinition of what we actually call a "disease", how we organize medicine and how we use Big Data to heal rather than treat and ideally to prevent diseases.He is a dedicated, international keynote speaker, podcaster, YouTuber and initiator of the German patientenwiewir.de patient platform. One of his hobbies is sports. For a long time, he was a soccer referee. His social engagement at Rotary International and different clubs introduced him to Homeless World Cup and sharpened is awareness and engagement for homeless people. Recently, his interested in sociocritical and political contemporary art recently started him to create his own small oeuvre under the concept of realitychanges.de, which has been selected for several solo and group exhibitions