Billions of people around the world are living with herpes infections, prompting the World Health Organization to call for a vaccine against the incurable virus. About half a billion people ages 15 to 49 have genital herpes infections, which are mostly caused by herpes simplex virus type 2, which can raise the risk of HIV. Herpes infections can lead to recurring, often painful, blisters. Genital herpes infections play a significant role in the spread of HIV globally according to report from World Health Organization.

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