Pauline, a young chambermaid who works at the legendary Mapes Hotel in Reno, Nevada, is asked to step in for a colleague and clean Suite 614. Although she was told the rooms were empty, a dazed, sleepy woman appears before her. This is Mrs. Miller, aka Marilyn Monroe, whose stay in Reno coincides with the breakdown of her marriage to Arthur Miller and the filming of what was to be her last film, The Misfits.

Set in the American West in 1960 where the mustang horses run wild, an unexpected friendship unfolds between the most famous movie star in the world and a young cleaning woman whose life will be changed forever through the course of a few weeks. A testament to the enduring power of female friendship and a reimagining of a side of Marilyn Monroe that has never been seen before.