Jolie Hoyt is a good Southern girl living in Hendrix, a small Florida Panhandle town. All too aware of her family's closet full of secrets and long-held distrust of outsiders, Jolie throws caution to the wind when she meets Sam Lense, a Jewish anthropology student from Miami, who is in town to study the ethnic makeup of the region.

Jolie and Sam fall recklessly in love, but their affair ends abruptly when Sam is discovered to have pried too deeply into Hendrix's dark racial history and he becomes the latest victim in a long tradition of small-town violence. Twelve years later, Jolie and Sam are forced to revisit the unresolved issues of their young love and finally shed light on the ugly history of Jolie's hometown. A complex and compulsively readable Southern saga, American Ghost is a richly woven exploration of how the events of our past haunt our present.