Jimmy Kudo, the son of a world-renowned mystery writer, is a high school detective who has cracked the most baffling of cases. One day while on a date with his childhood friend Rachel Moore, Jimmy observes a pair of men in black involved in some shady business. The men capture Jimmy and give him a poisonous substance to rub out their witness. But instead of killing him, it turns him into a little kid! Jimmy takes on the pseudonym Conan Edogawa and continues to solve all the difficult cases that come his way. All the while, he's looking for the men in black and the mysterious organization they're with in order to find a cure for his miniature malady.

Conan and Rachel take to the skies! But their transcontinental detective mission runs into unexpected turbulence when a murder is committed on board their passenger plane. Rachel doesn't think she can solve the case before the plane lands, but then she receives a little in-flight assistance...from none other than the long-lost Jimmy Kudo! Has Conan finally returned to his teenage self? And if so, how? Whatever the answer, Rachel's in for a bumpy flight!